Reinhart-King Laboratory

Publications

Quantifying Traction Stresses During Cell Migration
Kraning -Rush, C.M., S.P. Carey, J.P. Califano and C.A. Reinhart-King,
Methods in Cell Biology, in press.

Approaches to manipulating the dimensionality and physicochemical properties of common cellular scaffolds
Bajpai, S., N-Y Kim, C.A. Reinhart-King,
International Journal of Molecular Sciences, in press.

Mechanobiology of Tumor Invasion: where engineering meets oncology
Carey, S.P, T.M. D’Alfonso, S.J. Shin, C.A. Reinhart-King,
Clinical Reviews in Oncology and Hematology, in press.

Fabrication of substrates with defined mechanical properties and topographical features for the study of cell migration
Charest, J., J.P. Califano and C.A. Reinhart-King,
Macromolecular Bioscience, in press.

How Matrix Properties Control the Self-Assembly and Maintenance of Tissues
C.A. Reinhart-King
Annals of Biomedical Engineering, 2011,39(7):1849-56.

Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration
Huynh, J., K. Rana, N. Nozomi, JM Peloquin, JP Califano, CM Montague, C.B. Schaffer, M.R. King, C.A. Reinhart-King,
Science Translational Medicine, 2011, 3(112):112ra122.

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation
Heo, K., H. Lee, P. Nigro, T. Thomas, N. Le, E. Chang, C. McClain, C.A. Reinhart-King, M.R. King, B.C. Berk, K. Fujiwara, C. Woo, J. Abe,
Journal of Cell Biology, 2011, 193(5):867-84.

Cancer Cell Migration and Metastasis in the Microenvironment: A Tapered Microchannel Approach for Single Cell Studies
Mak, M., C.A. Reinhart-King and D. Erickson,
Plos One, 2011, 6(6):e20825.

Award Winning PictureIndentation Measurements of the Subendothelial Matrix in Bovine Carotid Arteries.
Peloquin, J.M., J. Huynh, R.M. Williams, C.A. Reinhart-King
Journal of Biomechanics, 2011, 44, 815-821.

The Role of the Cytoskeleton in Cellular Force Generation in 2D and 3D.
Kraning-Rush C., S.P. Carey, J.P. Califano, B.N. Smith and C.A. Reinhart-King
Physical Biology, 2011. 8(1):015009

Cell-Generated Forces in Tissue Assembly and Function
Huynh, J., Calfano, J.P., and C.A. Reinhart-King, Mechanobiology of Cell-Cell & Cell-Matrix Interactions ,
A.J. Wagoneer-Johnson and B. Harley (Ed.) Springer, 2011

Biodegradable Functional Poly(ester amide)s with Pendant Hydroxyl Functional Groups: Synthesis, Characterization, Fabrication and In Vitro Cellular Response.
Deng M, Wu J, Reinhart-King CA, Chu CC.
Acta Biomaterialia, 2011, 7(4):1504-15.

Forces During Cell Spreading and Adhesion
Carey, S, J. Charest, J., and C.A. Reinhart-King, Studies in Mechanobiology, Tissue Engineering and Biomaterials: Cellular and Biomolecular Mechanics and Mechanobiology
A. Gefen (Ed.), Springer, 2011.

Synthesis and characterization of functionalized water soluble cationic poly(ester amide)s
Pang, X., J. Wu, C.A. Reinhart-King, and C.C. Chu,
J. Polym. Sci. Part A: Polymer Chemistry, 2010 48(17): 3758-3766.

Synthesis, Characterization and Cytotoxicity of Photo-Crosslinked Maleic Chitosan– Polyethylene Glycol Diacrylate Hybrid Hydrogels
Zhong C., J. Wu, C.A. Reinhart-King and C. C. Chu
Acta Biomaterialia, 2010, 6(10): 3908-3918. 

Biological performance of biodegradable amino acid-based poly(ester amide)s: Endothelial cell adhesion and inflammation in vitro
Horwitz, J.A., K.M. Shum, J.C. Bodle, M. Deng, C.C. Chu, and C.A. Reinhart-King, 2010,
Journal of Biomedical Materials Research, 2010, 95(2):371-80.

Control of cell migration using a conducting polymer device
Gumus, A. J.P Califano, A.M.D. Wan, J. Huynh, C.A. Reinhart-King and G.G. Malliaras,
Soft Matter, 2010, 6: 5138-5142.

Substrate Stiffness and Cell Area Predict Cellular Traction Stresses in Single Cells and Cells in Contact
Califano, J.P. and C.A. Reinhart-King
Cellular and Molecular Engineering, 2010, 3(1): 68-75.  

The effects of substrate elasticity on endothelial cell network formation and traction force generation.

Califano JP, Reinhart-King CA.
Conf Proc IEEE Eng Med Biol Soc. 2009;1:3343-5. 

Synthesis and Characterization of biodegradable poly(ester amide)s with pendant amine function groups and in vitro cellular response
Deng, M., Wu, J., Reinhart-King, CA and C.C. Chu,
Biomacromolecules. 2009, 10(11):3037-47.

Exogenous and Endogenous Force Regulation of Endothelial Cells
Califano, J.P. and C.A. Reinhart-King
Journal of Biomechanics. 2010, 43(1):79-86 

A Balance of Chemistry and Mechanics Regulates Endothelial Network Formation
Califano, J.P. and C.A. Reinhart-King
Cell and Molecular Bioengineering, 2008. 1(2-3): p122-132.

Selected as an Outstanding Paper within the Cellular and Molecular Engineering Track at the 2008 Annual BMES meeting.

Endothelial Cell Adhesion and Migration
C.A. Reinhart-King
Methods in Enzymology, 2008; 443: 45-64.

Pre-Cornell

Physiologic Stress-Mediated Signaling in the Endothelium
Reinhart-King, CA, K. Fujiwara, B.C. Berk,
Methods in Enzymology, 2008; 443:25-44.

Cell-Cell Mechanical Communication through Compliant Substrates
Reinhart-King, C.A., M. Dembo, and D.A. Hammer
Biophysical Journal, 2008. 95(12): 6044-51.

Tensional Homeostasis and the Malignant Phenotype
Paszek, M.J., N. Zahir, K.R. Johnson, J.N. Lakins, G.I. Rozenberg, A. Gefen,
C.A. Reinhart-King, S.S. Margulies, M. Dembo, D. Boettiger, D.A. Hammer, V.M. Weaver
Cancer Cell, 2005. 8(3): 241-54. (Cover Article)

The Dynamics and Mechanics of Endothelial Cell Spreading
Reinhart-King, C.A., M. Dembo, and D.A. Hammer
Biophysical Journal, 2005. 89(1): 676-89.

Traction Forces Exerted by Adherent Cells
Reinhart-King, C.A. and D.A. Hammer,
Advances in Cellular Engineering: Understanding the Biomolecular Interface, 2005.
M.R. King (Ed.), Academic Press, New York: 3-24.

Dynamic Heterodimer-Functionalized Surfaces for Endothelial Cell Adhesion
Willcox, P.J., C.A. Reinhart-King, S.J. Lahr, and D.A. Hammer
Biomaterials, 2005. 26(23): 4757-66.

Endothelial Cell Traction Forces on RGD-Derivatized Polyacrylamide Substrata
Reinhart-King, C.A., M. Dembo, and D.A. Hammer, Langmuir, 2003. 19(5): 1573-1579.

The Role of Transient ERK2 Signals in Fibronectin- and Insulin-mediated DNA Synthesis
Asthagiri, A.R., C.A. Reinhart, A.F. Horwitz, and D.A. Lauffenburger
Journal of Cell Science, 2000. 113(24): 4499-510.

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